Bio-Rad Laboratories, Inc. NGC 100
Bio-Rad Laboratories, Inc. · Model NGC 100
The guided fluidics selection tool (patent pending), coupled with the module discovery system, enables a single-click application-based system setup through automated module function recognition. The Tier Rotate™ Feature allows optimal placement of valves and detectors to minimize the flow path. Compact footprint - fits in a refrigerator, lab bench, or coldroom. Point-to-Plumb™ Feature shows the step-by-step plumbing of the system using LEDs. ChromLab™ Software provides powerful system control, automated methods, and analysis options.
Key tips
- ·When no category-specific guidance fits, default to the manufacturer's own service manual and the general troubleshooting method in the Engineer's Guide.
- ·Run an incoming and annual electrical safety test regardless of how niche the device is.
Typical Failure Modes
Compiled for this model from its own documentation and established engineering knowledge for this equipment class - not from a verified service record. Confirm against the manufacturer's service manual.
Software cannot connect to the NGC instrument
HighSymptoms: ChromLab connection-failure message, no instrument control, touch screen shows no link.
Root cause: Wrong network name / IP, a firewall blocking ChromLab services, or a network / cabling fault between the PC and the instrument.
Pump flow / pressure instability
HighSymptoms: Unstable baseline, pressure spikes or a high-pressure trip, poor gradient reproducibility.
Root cause: Worn pump-head seals or check valves, air in the inlet lines, or a partially blocked in-line filter / column.
Buffer-blending / inlet valve fault
MediumSymptoms: Incorrect gradient, salt concentration off, valve not switching.
Root cause: Sticking or worn rotary inlet valve, or degraded valve tubing.
Detector (UV / conductivity) drift or noise
MediumSymptoms: Noisy or drifting signal, low lamp intensity warning, poor peak detection.
Root cause: Aged UV lamp, air bubble or contamination in the flow cell, or a fouled conductivity cell.
Module recognition failure
LowSymptoms: A stacked module is not detected by the discovery system, single-click setup fails.
Root cause: Module interconnect not seated, or a communication fault on that module.
Serviceable Parts & Consumables
Serviceable items for this model, compiled from its documentation and engineering knowledge for this equipment class. Service class and relative cost are estimates, not manufacturer figures; no part numbers are given. Confirm intervals and pricing against the manufacturer.
Pump-head seal and check-valve kit
Routine wear item on a chromatography pump.
Class Frequent wear itemRel. cost $$R&R Moderate
In-line / inlet filter set
Class Frequent wear itemRel. cost $R&R Fairly easy
Inlet / buffer-blend valve tubing kit
Class Frequent wear itemRel. cost $R&R Fairly easy
UV detector lamp
Class Periodic replacementRel. cost $$$R&R Moderate
Flow-cell / conductivity-cell assembly
Class Periodic replacementRel. cost $$$R&R Moderate
| Part | Service class | Relative cost | R&R difficulty |
|---|---|---|---|
| Pump-head seal and check-valve kit Routine wear item on a chromatography pump. | Frequent wear item | $$ | Moderate |
| In-line / inlet filter set | Frequent wear item | $ | Fairly easy |
| Inlet / buffer-blend valve tubing kit | Frequent wear item | $ | Fairly easy |
| UV detector lamp | Periodic replacement | $$$ | Moderate |
| Flow-cell / conductivity-cell assembly | Periodic replacement | $$$ | Moderate |
Relative cost: $ lowest · $$$$ highest service-part cost for this equipment class. Not a price.
PM Checklist
Preventive-maintenance tasks typical of this equipment class. Perform to the manufacturer's procedure and your facility's policy - this is general reference, not a schedule for this specific unit.
- ·Follow the manufacturer's PM schedule
- ·Perform incoming and annual electrical safety testing per facility biomedical program
Troubleshooting Approach
A starting sequence for this model, compiled from its documentation and engineering knowledge for this equipment class. Follow the manufacturer's service documentation for the actual procedure.
Symptom: ChromLab will not connect to the NGC system
- Verify the instrument is powered and on the network (ping it if possible).
- Confirm the exact Network Name or IP entered in ChromLab, then click Retry / Connect.
- Check the ChromLab PC firewall - ensure ChromLab programs and services are allowed.
- Swap the network cable and try a direct connection to isolate the switch.
- Once connected on the instrument touch screen, retry from the ChromLab computer.
Symptom: Unstable baseline or pressure
- Purge the pump and inlet lines to clear air.
- Replace the in-line filters and check for a blocked column.
- Run a pump seal / check-valve test; leaking or worn parts cause pressure ripple.
- Inspect the flow cell for bubbles or contamination and flush.
- Rebuild the pump head if seals are past their service interval.
Typical Location
Where this class of equipment is typically deployed - general reference, not this unit's own placement record.
- Varies by device - check the unit's own manual for facility placement guidance
Documents & Manuals
Safety & Recalls
Synced live from the FDA openFDA API.
- RECALL
It was discovered that the Variant II Turbo Link Calibrator Values card contains incorrect values for IFCC units. The numbers are missing a decimal point.
Troubleshoot this device with Bio
Describe a symptom or error code. Bio answers from this device's own documented error codes, failure modes, parts, and guides.
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